Ken Howard

Ken Howard

Company: Aarhus University

Job title: Associate Professor, Head of Bioengineered Drug Delivery Designs Laboratory iNANO


Physiologically Relevant Mouse Models to Investigate PK & Efficacy of HSA-Based Drugs 9:20 am

FcRn-driven cellular recycling facilitates the prolonged circulation of HSA  Models that maintain autologous HSA and human FcRn receptor (hFcRn) engagement are required to avoid competition from endogenous mouse albumin  Double transgenic HSA, hFcRn mice provides a physiological relevant environment and appropriate endogenous HSA competition to investigate recombinant HSA-drugs or conventional drugs whose PK is influenced by association with HSA Read more

day: Online Conference

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